Cancer Cells Employ Nuclear Caspase-8 to Overcome the p53-Dependent G2/M Checkpoint through Cleavage of USP28

limma powers differential expression analyses for RNA-sequencing and microarray studies

Matthew E. Ritchie, Belinda Phipson, Di Wu et al. · Nucleic Acids Research · 2015 · 40.9K citations · Full text

Genetics, Molecular Biology, Transcriptomics Technology +19

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data

Ethan Cerami, Jianjiong Gao, Uğur Doğrusöz et al. · Cancer Discovery · 2012 · 17.9K citations · Full text

voom: precision weights unlock linear model analysis tools for RNA-seq read counts

Charity W. Law, Yunshun Chen, Wei Shi et al. · Genome biology · 2014 · 6.4K citations · Full text

Catalytic activity of the caspase-8–FLIPL complex inhibits RIPK3-dependent necrosis

Andrew Oberst, Christopher P. Dillon, Ricardo Weinlich et al. · Nature · 2011 · 1.2K citations

Inflammation, Signal Transduction, Signaling Pathway +9

RIP3 mediates the embryonic lethality of caspase-8-deficient mice

William J. Kaiser, Jason W. Upton, Alyssa B. Long et al. · Nature · 2011 · 1K citations

Knockout Mouse, Embryonic Lethality, Apoptosis +5