Concepedia

Jason W. Upton

JW

34

Publications

7.2K

Citations

28

H-Index

1995

Active since

Affiliations

Emory University(Current)

The University of Texas at Austin

Auburn University

Washington University in St. Louis

The University of Texas Health Science Center at San Antonio

Jason W. Upton is an author at Emory University specializing in medicine, virology, and immunology.

Top concepts

MedicineVirologyImmunologyCell BiologyPathogenesisViral PathogenesisCell SignalingCell DeathApoptosisSepsis

Publications per year

1995–2025

34

Publications

34

RIP3 mediates the embryonic lethality of caspase-8-deficient mice

William J. Kaiser, Jason W. Upton, Alyssa B. Long et al. · Nature · 2011 · 1K citations

Knockout Mouse, Embryonic Lethality, Apoptosis +5

Toll-like Receptor 3-mediated Necrosis via TRIF, RIP3, and MLKL

William J. Kaiser, Haripriya Sridharan, Chunzi Huang et al. · Journal of Biological Chemistry · 2013 · 912 citations · Full text

Apoptosis, Immunology, Immune Regulation +23

DAI/ZBP1/DLM-1 Complexes with RIP3 to Mediate Virus-Induced Programmed Necrosis that Is Targeted by Murine Cytomegalovirus vIRA

Jason W. Upton, William J. Kaiser, Edward S. Mocarski · Cell Host & Microbe · 2012 · 740 citations · Full text

Molecular Virology, Pathogenesis, Viral Pathogenesis +9

RIP3 Induces Apoptosis Independent of Pronecrotic Kinase Activity

Pratyusha Mandal, Scott B. Berger, Sirika Pillay et al. · Molecular Cell · 2014 · 593 citations · Full text

Cell Regulation, Pronecrotic Kinase Activity, Receptor Tyrosine Kinase +6

Virus Inhibition of RIP3-Dependent Necrosis

Jason W. Upton, William J. Kaiser, Edward S. Mocarski · Cell Host & Microbe · 2010 · 553 citations · Full text

Virus Inhibition, Molecular Virology, Pathogenesis +5

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