Publication | Open Access

Physiologically based pharmacokinetic–pharmacodynamic modeling for prediction of vonoprazan pharmacokinetics and its inhibition on gastric acid secretion following intravenous/oral administration to rats, dogs and humans

Molecular PharmacologyPharmacokinetic ModelingPharmacodynamicsPharmacokinetic–pharmacodynamic ModelingGastrointestinal PharmacologyGastric Acid SecretionPhysiologyMedicineVonoprazan PharmacokineticsPharmacotherapyDrug AbsorptionPharmacologyPhysiologically-based Pharmacokinetic ModelingPharmacokineticsPharmacodynamic Modeling