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Changes in global gene expression indicate disordered autophagy, apoptosis and inflammatory processes and downregulation of cytoskeletal signalling and neuronal development in patients with Niemann–Pick C disease

Katarzyna Hetmańczyk-Sawicka, Roksana Iwanicka‐Nowicka, Anna Fogtman, Jarosław Cieśla, Paweł Włodarski, Barbara Żyżyńska‐Granica, Mirella Filocamo, Andrea Dardis, Paolo Peruzzo, Małgorzata Bednarska‐Makaruk,

Neurogenetics · 2020 · 20 citations · 49 references

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49

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

Damian Szklarczyk, Annika L. Gable, David Lyon et al. · Nucleic Acids Research · 2018 · 19.2K citations · Full text

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Causal analysis approaches in Ingenuity Pathway Analysis

A. Krämer, Jeff Green, Jack Pollard et al. · Bioinformatics · 2013 · 6.1K citations · Full text

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Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium

Emyr Lloyd‐Evans, Anthony J. Morgan, Xingxuan He et al. · Nature Medicine · 2008 · 833 citations

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Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol

Hyock Joo Kwon, Lina Abi-Mosleh, Michael Wang et al. · Cell · 2009 · 670 citations · Full text

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Cathepsin K-Dependent Toll-Like Receptor 9 Signaling Revealed in Experimental Arthritis

Masataka Asagiri, Toshitake Hirai, Toshihiro Kunigami et al. · Science · 2008 · 361 citations

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