Ex vivo expansion of regulatory T cells from long-term Belatacept-treated kidney transplant patients restores their phenotype and suppressive function but not their FOXP3 TSDR demethylation status

CTLA-4 Control over Foxp3 ⁺ Regulatory T Cell Function

Kajsa Wing, Yasushi Onishi, Paz Prieto-Martin et al. · Science · 2008 · 2.9K citations

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Epigenetic Control of the foxp3 Locus in Regulatory T Cells

Stefan Floess, Jennifer Freyer, Christiane Siewert et al. · PLoS Biology · 2007 · 1.2K citations · Full text

Life Sciences, Immunology, Molecular Biology +17

FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT

Yongqing Wu, Madhuri Borde, Vigo Heissmeyer et al. · Cell · 2006 · 1.2K citations · Full text

Life Sciences, Immunology, Molecular Biology +10

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

Claudio G. Brunstein, Jeffrey S. Miller, Qing Cao et al. · Blood · 2010 · 1K citations · Full text

Life Sciences, Hematology, Immunology +17

A Phase III Study of Belatacept‐based Immunosuppression Regimens versus Cyclosporine in Renal Transplant Recipients (BENEFIT Study)

Flavio Vincenti, B Charpentier, Yves Vanrenterghem et al. · American Journal of Transplantation · 2010 · 946 citations

Medicine, Nephrology, Pharmacology +15