Concepedia

Differential protein phosphorylation is responsible for hypoxia-induced regulation of the Akt/mTOR pathway in naked mole rats

Rasha Al-attar, Christine L. Childers, Vu Chau Nguyen, Matthew E. Pamenter, Kenneth B. Storey

Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · 2020 · 22 citations · 47 references

DOI

Concepts

References

47

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

Ken Inoki, Yong Li, Tianquan Zhu et al. · Nature Cell Biology · 2002 · 3.1K citations

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IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

Martin Holzenberger, Joëlle Dupont, Bertrand Ducos et al. · Nature · 2002 · 2.1K citations · Full text

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Rheb Binds and Regulates the mTOR Kinase

Yenshou Lin, Sara Ortiz-Vega, Kazuyoshi Yonezawa et al. · Current Biology · 2005 · 990 citations · Full text

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Roles of Growth Hormone and Insulin-like Growth Factor 1 in Mouse Postnatal Growth

Floria Lupu, Joseph D. Terwilliger, Kaechoong Lee et al. · Developmental Biology · 2001 · 772 citations

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Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat

Thomas J. Park, Jane Reznick, Bethany L. Peterson et al. · Science · 2017 · 650 citations · Full text

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