Concepedia

Metabolic heterogeneity confers differences in melanoma metastatic potential

Alpaslan Tasdogan, Brandon Faubert, Vijayashree Ramesh, Jessalyn M. Ubellacker, Bo Shen, Ashley Solmonson, Malea M. Murphy, Zhimin Gu, Wen Gu, Misty Martin,

Nature · 2019 · 487 citations · 38 references

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38

Genome engineering using the CRISPR-Cas9 system

F. Ann Ran, Patrick D. Hsu, Jason Wright et al. · Nature Protocols · 2013 · 11.4K citations · Full text

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Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

Gina M. DeNicola, Florian A. Karreth, Timothy J. Humpton et al. · Nature · 2011 · 2.2K citations · Full text

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Glucose feeds the TCA cycle via circulating lactate

Sheng Hui, Jonathan M. Ghergurovich, Raphael J. Morscher et al. · Nature · 2017 · 1.6K citations · Full text

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Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

Pierre Sonveaux, Frédérique Végran, Thies Schroeder et al. · Journal of Clinical Investigation · 2008 · 1.6K citations · Full text

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Lactate Metabolism in Human Lung Tumors

Brandon Faubert, Kevin Y. Li, Ling Cai et al. · Cell · 2017 · 1.3K citations · Full text

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