Histone deacetylase 6 inhibition restores autophagic flux to promote functional recovery after spinal cord injury

HDAC6 is a microtubule-associated deacetylase

Charlotte Hubbert, Amaris R. Guardiola, Rong Shao et al. · Nature · 2002 · 2.4K citations

Life Sciences, Biochemistry, Molecular Biology +5

The Deacetylase HDAC6 Regulates Aggresome Formation and Cell Viability in Response to Misfolded Protein Stress

Yoshiharu Kawaguchi, Jeffrey J. Kovacs, Adam C. McLaurin et al. · Cell · 2003 · 1.5K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

The Hairpin-type Tail-Anchored SNARE Syntaxin 17 Targets to Autophagosomes for Fusion with Endosomes/Lysosomes

Eisuke Itakura, Chieko Kishi‐Itakura, Noboru Mizushima · Cell · 2012 · 1.3K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

Joan S. Steffan, László Bodai, Judit Pallos et al. · Nature · 2001 · 1.2K citations · Full text

Life Sciences, Molecular Biology, Neuroscience +14

HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

Udai Bhan Pandey, Zhiping Nie, Yakup Batlevi et al. · Nature · 2007 · 1.2K citations

Life Sciences, Cell Biology, Neuroscience +12