Concepedia

The Deacetylase HDAC6 Regulates Aggresome Formation and Cell Viability in Response to Misfolded Protein Stress

Yoshiharu Kawaguchi, Jeffrey J. Kovacs, Adam C. McLaurin, Jeffery M. Vance, Akihiro Ito, Tso-Pang Yao

Cell · 2003 · 1.5K citations · 18 references

DOIFull text

Open access

Concepts

References

18

HDAC6 is a microtubule-associated deacetylase

Charlotte Hubbert, Amaris R. Guardiola, Rong Shao et al. · Nature · 2002 · 2.4K citations

, , +5

Aggresomes: A Cellular Response to Misfolded Proteins

Jennifer Johnston, Cristina L. Ward, Ron R. Kopito · The Journal of Cell Biology · 1998 · 2.2K citations · Full text

, , +17

Degradation of CFTR by the ubiquitin-proteasome pathway

Cristina L. Ward, Satoshi ŌMURA, Ron R. Kopito · Cell · 1995 · 1.3K citations · Full text

, , +17

Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation

Stephen J. Haggarty, Kathryn M. Koeller, Jason Chun Yu Wong et al. · Proceedings of the National Academy of Sciences · 2003 · 1.1K citations · Full text

, , +12

Multiple proteolytic systems, including the proteasome, contribute to CFTR processing

Timothy J. Jensen, Melinda A. Loo, S. Pind et al. · Cell · 1995 · 898 citations · Full text

, , +12