Concepedia

Pharmacokinetics of Organic Cation Transporter 1 (OCT1) Substrates in Oct1/2 Knockout Mice and Species Difference in Hepatic OCT1-Mediated Uptake

Bridget L. Morse, Anil Kolur, Loyd Hudson, Andrew T. Hogan, Lisa Hong Chen, Ryan M. Brackman, Geri A. Sawada, John K. Fallon, Philip C. Smith, Kathleen M. Hillgren

Drug Metabolism and Disposition · 2019 · 34 citations · 30 references

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References

30

Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action

Yan Shu, Steven A. Sheardown, Chaline Brown et al. · Journal of Clinical Investigation · 2007 · 958 citations · Full text

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Effect of Genetic Variation in the Organic Cation Transporter 1, OCT1, on Metformin Pharmacokinetics

C. Randell Brown, R A Castro, RJ Shi et al. · Clinical Pharmacology & Therapeutics · 2007 · 467 citations

, , +15

Involvement of Organic Cation Transporter 1 in Hepatic and Intestinal Distribution of Metformin

Desheng Wang, Johan W. Jonker, Yukio Kato et al. · Journal of Pharmacology and Experimental Therapeutics · 2002 · 442 citations

, , +17

Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes

Nature Genetics · 2010 · 430 citations · Full text

, , +11

Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1

Yan Shu, Maya K. Leabman, Bo Feng et al. · Proceedings of the National Academy of Sciences · 2003 · 284 citations

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