Concepedia

Transcription-independent Induction of ERBB1 through Hypoxia-inducible Factor 2A Provides Cardioprotection during Ischemia and Reperfusion

Jae W. Lee, Michael Koeppen, Seong-Wook Seo, Jessica L. Bowser, Xiaoyi Yuan, Jiwen Li, Maria Sibilia, Amrut V. Ambardekar, Xu Zhang, Tobias Eckle,

Anesthesiology · 2019 · 33 citations · 39 references

DOIFull text

Open access

Abstract

These findings suggest that hypoxia-inducible factor 2A promotes transcription-independent induction of ERBB1 protein and implicates epidermal growth factor signaling in protection from myocardial ischemia and reperfusion injury.

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39

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