Concepedia

STAT3-miR-17/20 signalling axis plays a critical role in attenuating myocardial infarction following rapamycin treatment in diabetic mice

Arun Samidurai, Sean K. Roh, Meeta Prakash, David Durrant, Fadi N. Salloum, Rakesh C. Kukreja, Anindita Das

Cardiovascular Research · 2019 · 26 citations · 53 references

DOIFull text

Open access

Abstract

Induction of STAT3-miRNA-17-92 signalling axis plays a critical role in attenuating MI in RAPA-treated diabetic mice. Our study indicates that chronic treatment with RAPA might be a promising pharmacological intervention for attenuating MI and improving prognosis in diabetic patients.

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