Indazolyl-substituted piperidin-4-yl-aminopyrimidines as HIV-1 NNRTIs: Design, synthesis and biological activities

Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds

Rudi Pauwels, Jan Balzarini, Masanori Baba et al. · Journal of Virological Methods · 1988 · 1.6K citations

Medicinal Chemistry, Bioassay-guided Isolation, Tetrazolium-based Colorimetric Assay +12

Surflex:  Fully Automatic Flexible Molecular Docking Using a Molecular Similarity-Based Search Engine

Ajay N. Jain · Journal of Medicinal Chemistry · 2003 · 1.3K citations

Scoring noncovalent protein-ligand interactions: A continuous differentiable function tuned to compute binding affinities

Ajay N. Jain · Journal of Computer-Aided Molecular Design · 1996 · 602 citations

Protein Folding, Medicine, Molecular Biology +9

Hammerhead: fast, fully automated docking of flexible ligands to protein binding sites

William H. Welch, Jim Ruppert, Ajay N. Jain · Chemistry & Biology · 1996 · 363 citations · Full text

Protein Assembly, Protein Folding, Medicine +9

Tetrazolium-based colorimetric assay for the detection of HIV replication inhibitors: revisited 20 years later

Christophe Pannecouque, Dirk Daelemans, Erik De Clercq · Nature Protocols · 2008 · 347 citations

Hiv Replication Inhibitors, Medicinal Chemistry, Medicine +13