Amentoflavone suppresses amyloid β1–42 neurotoxicity in Alzheimer's disease through the inhibition of pyroptosis

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

Edward A. Miao, Irina A. Leaf, Piper M. Treuting et al. · Nature Immunology · 2010 · 1.3K citations · Full text

Life Sciences, Immunology, Microbiology +16

Shigella flexneri induces apoptosis in infected macrophages

Arturo Zychlinsky, M.C. Prévost, Philippe Sansonetti · Nature · 1992 · 1.2K citations

Life Sciences, Immunology, Microbiology +9

Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice

Richard D. Gordon, Eduardo A. Albornoz, Daniel C. Christie et al. · Science Translational Medicine · 2018 · 890 citations

Life Sciences, Neurology, Neuroscience +17

Inhibiting the NLRP3 inflammasome with MCC950 promotes non-phlogistic clearance of amyloid-β and cognitive function in APP/PS1 mice

Colin Dempsey, Karen Bryson, Orla M. Finucane et al. · Brain Behavior and Immunity · 2016 · 568 citations

Life Sciences, Neurobiology, Neuroscience +15

The neuroprotective potential of flavonoids: a multiplicity of effects

David Vauzour, Katerina Vafeiadou, Ana Rodriguez‐Mateos et al. · Genes & Nutrition · 2008 · 550 citations · Full text

Medicine, Neuroscience, Pharmacology +12