The KDEL receptor has a role in the biogenesis and trafficking of the epithelial sodium channel (ENaC)

Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice

Marcus Mall, Barbara R. Grubb, Jack R. Harkema et al. · Nature Medicine · 2004 · 892 citations

Inflammation, Fibrosis, Allergy +9

WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome.

Olivier Staub, Sascha E. Dho, P Henry et al. · The EMBO Journal · 1996 · 841 citations · Full text

Nedd4 Bind, Protein Function, Molecular Physiology +12

Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na+ channel cell surface expression

Christophe Debonneville · The EMBO Journal · 2001 · 701 citations · Full text

Signal Transduction, Molecular Physiology, Signaling Pathway +8

Visualization of ER-to-Golgi Transport in Living Cells Reveals a Sequential Mode of Action for COPII and COPI

Suzie J. Scales, Rainer Pepperkok, Thomas E. Kreis · Cell · 1997 · 505 citations · Full text

Golgi Apparatus, Signal Transduction, Organelle Dynamic +13

Ligand-induced redistribution of a human KDEL receptor from the Golgi complex to the endoplasmic reticulum

Michael Lewis, Hugh R.B. Pelham · Cell · 1992 · 401 citations

Ligand-induced Redistribution, Golgi Apparatus, Signal Transduction +14