Publication | Closed Access
Lysosome-targeted iridium(<scp>iii</scp>) compounds with pyridine-triphenylamine Schiff base ligands: syntheses, antitumor applications and mechanisms
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Citations
46
References
2019
Year
Molecular BiologyCell DeathLysosomal DamageChemical BiologyPharmaceutical ChemistryInorganic CompoundPyridine-triphenylamine Schiff BaseMedicinal ChemistryAntitumor ApplicationsAnti-cancer AgentLysosome-targeted IridiumInorganic ChemistryHalf-sandwiched IridiumBiochemistrySchiff Base ComplexesDrug TargetingNatural SciencesCoordination ComplexMolecular ComplexMedicineDrug Discovery
Half-sandwiched iridium(<sc>iii</sc>) Schiff base complexes showed potential antitumor activity and could induce apoptosis through metastasis inhibition and lysosomal damage.
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