Concepedia

Lysosome-targeted iridium(<scp>iii</scp>) compounds with pyridine-triphenylamine Schiff base ligands: syntheses, antitumor applications and mechanisms

Shujiao Chen, Xicheng Liu, Xingxing Ge, Qinghui Wang, Yaoqi Xie, Yingying Hao, Ying Zhang, Lei Zhang, Wenjing Shang, Zhe Liu

Inorganic Chemistry Frontiers · 2019 · 50 citations · 46 references

DOI

Concepts

Abstract

Half-sandwiched iridium(<sc>iii</sc>) Schiff base complexes showed potential antitumor activity and could induce apoptosis through metastasis inhibition and lysosomal damage.

References

46

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A Nonemissive Iridium(III) Complex That Specifically Lights-Up the Nuclei of Living Cells

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