Concepedia

Lysosomal Damage Response

Lysosomal Damage Response is a cellular surveillance mechanism that detects and repairs compromised lysosomes by selectively recruiting autophagy-related proteins and effectors to the damaged organelle, thereby maintaining lysosomal homeostasis and preventing cytotoxic leakage.

139

Publications

9.2K

Citations

798

Authors

247

Institutions

Publications per year

2017–2026

63

Parents

Publications

139

MECHANISMS OF LYSOSOMAL ENZYME RELEASE FROM LEUKOCYTES EXPOSED TO IMMUNE COMPLEXES AND OTHER PARTICLES

Gerald Weissmann, Robert B. Zurier, Paul J. Spieler et al. · The Journal of Experimental Medicine · 1971 · 435 citations

, , +13

Contaminant-induced lysosomal membrane damage in blood cells of mussels Mytilus galloprovincialis from the Venice Lagoon:an in vitro study

D. Lowe, VU Fossato · Marine Ecology Progress Series · 1995 · 327 citations · Full text

, , +11

Antitumor Activity of Metal-Chelating Compound Dp44mT Is Mediated by Formation of a Redox-Active Copper Complex That Accumulates in Lysosomes

David B. Lovejoy, Patric J. Jansson, Ulf T. Brunk et al. · Cancer Research · 2011 · 305 citations

, , +17

Contaminant induced lysosomal membrane damage in marine mussel digestive cells: an in vitro study

D.M. Lowe, R.K. Pipe · Aquatic Toxicology · 1994 · 281 citations

, , +16

Plasma membrane damage causes NLRP3 activation and pyroptosis during Mycobacterium tuberculosis infection

Kai Sandvold Beckwith, Marianne Sandvold Beckwith, Sindre Ullmann et al. · Nature Communications · 2020 · 274 citations · Full text

, , +17

1–5 of 139

Authors

798

  1. UT
    Ulf T. Brunk

    Linköping University, Sweden

    11 publications · 1.3K citations

    10

    h-index

  2. ZL
    Zhe Liu

    Qufu Normal University, China

    6 publications · 161 citations

    6

    h-index

  3. CB
    Christian Behrends

    Ludwig-Maximilians-Universität München, Germany

    6 publications · 554 citations

    6

    h-index

  4. XL
    Xicheng Liu

    Qufu Normal University, China

    5 publications · 143 citations

    5

    h-index

  5. JJ
    Jingyue Jia

    University of New Mexico, United States

    5 publications · 374 citations

    5

    h-index

1–5 of 798

Institutions

247

  1. Linköping University

    Linköping, Sweden

    10 h-index

    29 publications

    3.7K citations

  2. Munich Cluster for Systems Neurology

    Munich, Germany

    6 h-index

    11 publications

    1.1K citations

  3. Qufu Normal University

    Qufu, China

    6 h-index

    61 publications

    1.7K citations

  4. University of New Mexico

    Albuquerque, United States

    5 h-index

    45 publications

    3.1K citations

  5. Ludwig-Maximilians-Universität München

    Munich, Germany

    5 h-index

    9 publications

    738 citations

  6. University of Southern California

    Los Angeles, United States

    4 h-index

    6 publications

    1.1K citations

  7. Universidade de São Paulo

    São Paulo, Brazil

    4 h-index

    27 publications

    2.9K citations

  8. University of California, Davis

    Davis, United States

    4 h-index

    7 publications

    317 citations

1–8 of 247

Venues

  1. Autophagy

    6 publications · 333 citations

    6

    h-index

  2. The Journal of Immunology

    JI · 4 publications · 172 citations

    4

    h-index

  3. The Journal of Cell Biology

    JCB · 4 publications · 386 citations

    4

    h-index

  4. The EMBO Journal

    3 publications · 285 citations

    3

    h-index

  5. Canadian Journal of Microbiology

    3 publications · 45 citations

    3

    h-index

1–5