Concepedia

Lysosomal Activation

Lysosomal Activation is a pH-activated prodrug strategy that exploits the acidic environment of lysosomes to selectively trigger the intracellular release of active therapeutic agents.

529

Publications

29.1K

Citations

2.5K

Authors

758

Institutions

Publications per year

2017–2026

119

Parents

Publications

529

Activation of Chaperone-mediated Autophagy during Oxidative Stress

Roberta Kiffin, Christopher Christian, Erwin Knecht et al. · Molecular Biology of the Cell · 2004 · 603 citations · Full text

, , +17

Defective cholesterol clearance limits remyelination in the aged central nervous system

Ludovico Cantuti‐Castelvetri, Dirk Fitzner, Mar Bosch-Queralt et al. · Science · 2018 · 575 citations · Full text

, , +17

Mechanisms of Lysosomal Enzyme Release from Human Leukocytes II. EFFECTS OF cAMP AND cGMP, AUTONOMIC AGONISTS, AND AGENTS WHICH AFFECT MICROTUBULE FUNCTION

Robert B. Zurier, Gerald Weissmann, Sylvia Hoffstein et al. · Journal of Clinical Investigation · 1974 · 562 citations · Full text

, , +15

The Toll‐like receptor 7 (TLR7)‐specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily

Florian Heil, Parviz Ahmad‐Nejad, Hiroaki Hemmi et al. · European Journal of Immunology · 2003 · 515 citations · Full text

, , +17

MECHANISMS OF LYSOSOMAL ENZYME RELEASE FROM LEUKOCYTES EXPOSED TO IMMUNE COMPLEXES AND OTHER PARTICLES

Gerald Weissmann, Robert B. Zurier, Paul J. Spieler et al. · The Journal of Experimental Medicine · 1971 · 435 citations

, , +13

1–5 of 529

Authors

2.5K

  1. PM
    Paul M. Tulkens

    UCLouvain, Belgium

    14 publications · 638 citations

    13

    h-index

  2. UT
    Ulf T. Brunk

    Linköping University, Sweden

    11 publications · 1.8K citations

    11

    h-index

  3. GW
    Gerald Weissmann

    New York University, United States

    10 publications · 2K citations

    10

    h-index

  4. JP
    Jocelyne Piret

    Université Laval, Canada

    6 publications · 165 citations

    6

    h-index

  5. LJ
    Louis J. Ignarro

    University of California, Los Angeles, United States

    6 publications · 201 citations

    6

    h-index

1–5 of 2.5K

Institutions

758

  1. Linköping University

    Linköping, Sweden

    13 h-index

    45 publications

    7.3K citations

  2. Inserm

    Paris, France

    12 h-index

    58 publications

    3.2K citations

  3. UCLouvain

    Louvain-la-Neuve, Belgium

    12 h-index

    48 publications

    1.4K citations

  4. New York University

    New York, United States

    9 h-index

    26 publications

    6.4K citations

  5. Chinese Academy of Medical Sciences & Peking Union Medical College

    Beijing, China

    7 h-index

    55 publications

    2.6K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    7 h-index

    43 publications

    2.3K citations

  7. Chinese Academy of Sciences

    Beijing, China

    6 h-index

    21 publications

    1K citations

  8. Tulane University

    New Orleans, United States

    6 h-index

    15 publications

    681 citations

1–8 of 758

Venues

  1. PubMed

    Repository · 35 publications · 1.9K citations

    21

    h-index

  2. Biochemical Pharmacology

    21 publications · 942 citations

    16

    h-index

  3. Journal of Biological Chemistry

    JBC · 11 publications · 662 citations

    11

    h-index

  4. The Journal of Immunology

    JI · 12 publications · 720 citations

    11

    h-index

  5. Scientific Reports

    10 publications · 489 citations

    10

    h-index

1–5