Microorganisms · 2019 · 16 citations · 19 references
AgricultureFood ScienceMicrobiologyFood AnalysisFood MicrobiologyMedical MicrobiologyMicrobial QualityMicrobiological QualityOral ProbioticsProbioticsProbiotics In FoodsEscherichia ColiLabel Claims SubstantiationOral Nutrition SupplementsProbiotic Safety AssessmentProbiotic SupplementsSafety Of Oral ProbioticsStomach ModelingViability Of Probiotic Bacteria
Probiotic products typically take the form of oral supplements or food-based products containing microorganisms, typically bacteria. The number of bacteria present in a dose of probiotic can be several orders of magnitude lower than the label claims, and in some cases, undetectable. The objective of this study was to assess probiotic products containing Escherichia coli to verify manufacturer claims, which have not yet been independently assessed, regarding the number of viable E. coli per suggested dose. It was found that the products tested contained E. coli in numbers several orders of magnitude less than claimed, and when subjected to simulated stomach conditions, the number of viable E. coli was significantly reduced.
19
A human gut microbial gene catalogue established by metagenomic sequencing
Junjie Qin, Ruiqiang Li, Jeroen Raes et al. · Nature · 2010 · 11.7K citations · Full text