Concepedia

Development of a High-Throughput Fluorescence Polarization Assay to Detect Inhibitors of the FAK–Paxillin Interaction

Timothy Marlowe, Carlos Alvarado, Andrew Rivera, Felicia L. Lenzo, Rohini Nott, Dena Bondugji, Justin J. Montoya, Alana Hurley, Matt Kaplan, Andrew P. Capaldi,

SLAS DISCOVERY · 2019 · 10 citations · 35 references

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Concepts

References

35

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

Ji-Hu Zhang, Thomas D.Y. Chung, Kevin R. Oldenburg · SLAS DISCOVERY · 1999 · 7K citations · Full text

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New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays

Jonathan B. Baell, Georgina A. Holloway · Journal of Medicinal Chemistry · 2010 · 3.9K citations

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Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

Duško llić, Yasuhide Furuta, S. Kanazawa et al. · Nature · 1995 · 1.8K citations

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pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.

Michael D. Schaller, Cheryl A. Borgman, Bradley S. Cobb et al. · Proceedings of the National Academy of Sciences · 1992 · 1.4K citations

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FAK integrates growth-factor and integrin signals to promote cell migration

David J. Sieg, Christof R. Hauck, Duško Ilić et al. · Nature Cell Biology · 2000 · 1.2K citations · Full text

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