Novel discovery of Averrhoa bilimbi ethanolic leaf extract in the stimulation of brown fat differentiation program in combating diet-induced obesity

PRDM16 controls a brown fat/skeletal muscle switch

Patrick Seale, Bryan C. Bjork, Wenli Yang et al. · Nature · 2008 · 2.3K citations · Full text

Muscle Function, Signal Transduction, Molecular Physiology +3

PPARγ agonists Induce a White-to-Brown Fat Conversion through Stabilization of PRDM16 Protein

Haruya Ohno, Kosaku Shinoda, Bruce M. Spiegelman et al. · Cell Metabolism · 2012 · 726 citations · Full text

Metabolic Syndrome, Signal Transduction, Lipid Synthesis +7

Prdm16 Is Required for the Maintenance of Brown Adipocyte Identity and Function in Adult Mice

Matthew Harms, Jeff Ishibashi, Wenshan Wang et al. · Cell Metabolism · 2014 · 382 citations · Full text

Obesity, Metabolic Syndrome, Energy Homeostasis +11

Importance of the bioenergetic reserve capacity in response to cardiomyocyte stress induced by 4-hydroxynonenal

Bradford G. Hill, Brian P. Dranka, Luyun Zou et al. · Biochemical Journal · 2009 · 283 citations · Full text

Cardiac Muscle, Heart Failure, Lipid Peroxidation +20

Effects of Averrhoa bilimbi leaf extract on blood glucose and lipids in streptozotocin-diabetic rats

Peter Natesan Pushparaj, C.H. Tan, B.K.H. Tan · Journal of Ethnopharmacology · 2000 · 269 citations

Medicine, Physiology, Diabetes +7