PRDM16 controls a brown fat/skeletal muscle switch

Patrick Seale, Bryan C. Bjork, Wenli Yang, +11

Nature

Muscle FunctionSignal TransductionMolecular PhysiologySkeletal MusclePhysiology +1

Pax7 Is Required for the Specification of Myogenic Satellite Cells

Patrick Seale, Luc A. Sabourin, Adele Girgis-Gabardo, +2

Cell

Myogenic Satellite CellsMedicineSystems BiologyCell EngineeringCell Biology

Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice

Patrick Seale, Heather M. Conroe, Jennifer L. Estall, +6

Journal of Clinical Investigation

Metabolic DisorderAdipokinesInsulin SignalingObesityMetabolic Syndrome +20

Transcriptional Control of Brown Fat Determination by PRDM16

Patrick Seale, Shingo Kajimura, Wenli Yang, +6

Cell Metabolism

Transcriptional RegulationSystems BiologyMetabolic RegulationGene ExpressionMedicine +1

Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity

Jonathan R. Brestoff, Brian Kim, Steven A. Saenz, +8

Nature

ObesityMetabolic SyndromeInflammationGroup 2Energy Homeostasis +13

Ablation of PRDM16 and Beige Adipose Causes Metabolic Dysfunction and a Subcutaneous to Visceral Fat Switch

Paul Cohen, Julia D. Levy, Yingying Zhang, +19

Cell

ObesityMetabolic SyndromeBody CompositionMetabolic DisorderAdipose Tissue +11

Initiation of myoblast to brown fat switch by a PRDM16–C/EBP-β transcriptional complex

Shingo Kajimura, Patrick Seale, Kazuishi Kubota, +4

Nature

Transcriptional RegulationSignaling PathwayProtein ExpressionFat SwitchPrdm16–c/ebp-β Transcriptional Complex +10

Myogenic specification of side population cells in skeletal muscle

Atsushi Asakura, Patrick Seale, Adele Girgis-Gabardo, +1

The Journal of Cell Biology

Identification of a mesenchymal progenitor cell hierarchy in adipose tissue

David Merrick, Alexander P. Sakers, Zhazira Irgebay, +5

Science

Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation

Marc Uldry, Wenli Yang, Julie St‐Pierre, +3

Cell Metabolism

Mitochondrial BiogenesisMitochondrial FunctionBiochemistryBrown Fat DifferentiationMetabolic Regulation +6