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Discovery of potent 4-aminoquinoline hydrazone inhibitors of NRH:quinoneoxidoreductase-2 (NQO2)

Buthaina Hussein, Balqis Ikhmais, Manikandan Kadirvel, Rachael N. Magwaza, Gavin Halbert, Richard A. Bryce, Ian J. Stratford, Sally Freeman

European Journal of Medicinal Chemistry · 2019 · 18 citations · 30 references

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Improved protein–ligand docking using GOLD

Marcel L. Verdonk, Jason C. Cole, Michael J. Hartshorn et al. · Proteins Structure Function and Bioinformatics · 2003 · 3K citations · Full text

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Synthesis and anti-tubercular evaluation of 4-quinolylhydrazones

Luisa Savini, Luisa Chiasserini, Alessandra Gaeta et al. · Bioorganic & Medicinal Chemistry · 2002 · 133 citations

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An Association between Idiopathic Parkinson's Disease and Polymorphisms of Phase II Detoxification Enzymes: Glutathione S-Transferase M1 and Quinone Oxidoreductase 1 and 2

Shoji Harada, Chieko Fujii, Akito Hayashi et al. · Biochemical and Biophysical Research Communications · 2001 · 126 citations

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Synthesis of ring-substituted 4-aminoquinolines and evaluation of their antimalarial activities

Peter B. Madrid, John Sherrill, Ally P. Liou et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 117 citations

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Bioactivation of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) by human NAD(P)H quinone oxidoreductase 2: a novel co-substrate-mediated antitumor prodrug therapy.

Richard J. Knox, Terence C. Jenkins, Stephen M. Hobbs et al. · PubMed · 2000 · 117 citations

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