Concepedia

Serum bicarbonate and cardiovascular events in hypertensive adults: results from the Systolic Blood Pressure Intervention Trial

Mirela Dobre, Nicholas M. Pajewski, Srinivasan Beddhu, Michel Chonchol, Thomas H. Hostetter, Ping Li, Mahboob Rahman, Karen S. Servilla, Daniel E. Weiner, Jackson T. Wright,

Nephrology Dialysis Transplantation · 2019 · 28 citations · 27 references

DOIFull text

Open access

Abstract

In hypertensive individuals, serum bicarbonate level <22 mEq/L was associated with an increased CVD risk. The effect of intensive BP lowering on CVD outcomes was not modified by the serum bicarbonate level.

References

27

Magnesium Replacement Improves the Metabolic Profile in Obese and Pre-Diabetic Patients with Mild-to-Moderate Chronic Kidney Disease: A 3-Month, Randomised, Double-Blind, Placebo-Controlled Study

Ömer Toprak, Hüseyin Kurt, Yasin Sarı et al. · Kidney & Blood Pressure Research · 2017 · 29.7K citations · Full text

A New Equation to Estimate Glomerular Filtration Rate

Andrew S. Levey, Lesley A. Stevens, Christopher H. Schmid et al. · Annals of Internal Medicine · 2009 · 25K citations

A Randomized Trial of Intensive versus Standard Blood-Pressure Control

New England Journal of Medicine · 2015 · 6K citations · Full text

Low Heart Rate Variability in a 2-Minute Rhythm Strip Predicts Risk of Coronary Heart Disease and Mortality From Several Causes

Richard S. Crow, Aaron R. Folsom, Peter J. Hannan et al. · Circulation · 2000 · 838 citations · Full text

The design and rationale of a multicenter clinical trial comparing two strategies for control of systolic blood pressure: The Systolic Blood Pressure Intervention Trial (SPRINT)

Walter T. Ambrosius, Kaycee M. Sink, Capri G. Foy et al. · Clinical Trials · 2014 · 531 citations · Full text