Development of novel theranostic agents for in vivo amyloid imaging and protective effects on human neuroblastoma cells

Iterative partial equalization of orbital electronegativity—a rapid access to atomic charges

Johann Gasteiger, Mario Marsili · Tetrahedron · 1980 · 4.1K citations

Physics, Electron Spectroscopy, Natural Sciences +5

Validation of the general purpose tripos 5.2 force field

Matthew Clark, Richard D. Cramer, N. Van Opdenbosch · Journal of Computational Chemistry · 1989 · 2.8K citations

Engineering, Computational Chemistry, Verification And Validation +18

Natural oligomers of the amyloid-β protein specifically disrupt cognitive function

James Cleary, Dominic M. Walsh, J. Hofmeister et al. · Nature Neuroscience · 2004 · 1.7K citations

Neurodegenerative Diseases, Molecular Neuroscience, Molecular Biology +5

Amyloid β-protein (Aβ) assembly: Aβ40 and Aβ42 oligomerize through distinct pathways

Gal Bitan, Marina Kirkitadze, Aleksey Lomakin et al. · Proceedings of the National Academy of Sciences · 2002 · 1.3K citations · Full text

Protein Assembly, Molecular Biology, Neurochemical Biomarkers +19

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

P. Hemachandra Reddy, M. Flint Beal · Trends in Molecular Medicine · 2008 · 942 citations · Full text

Alzheimer's Disease, Aging, Mitochondrial Dysfunction +10