Huixiong Chen

Phosphinic Derivatives as New Dual Enkephalin-Degrading Enzyme Inhibitors: Synthesis, Biological Properties, and Antinociceptive Activities

Huixiong Chen, Florence Noble, Aurélie Mothé et al. · Journal of Medicinal Chemistry · 2000 · 83 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Development of Phenothiazine-Based Theranostic Compounds That Act Both as Inhibitors of β-Amyloid Aggregation and as Imaging Probes for Amyloid Plaques in Alzheimer’s Disease

Pascal Dao, Feifei Ye, Yan Liu et al. · ACS Chemical Neuroscience · 2017 · 79 citations

Medicine, Neuroscience, Pharmacology +17

Synthesis of carbazole derivatives containing chalcone analogs as non-intercalative topoisomerase II catalytic inhibitors and apoptosis inducers

Penghui Li, Hong Jiang, Wenjin Zhang et al. · European Journal of Medicinal Chemistry · 2018 · 67 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Aminophosphinic inhibitors as transition state analogues of enkephalin-degrading enzymes: A class of central analgesics

Huixiong Chen, Florence Noble, Pascale Coric et al. · Proceedings of the National Academy of Sciences · 1998 · 64 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Synthesis of novel diarylamino-1,3,5-triazine derivatives as FAK inhibitors with anti-angiogenic activity

Pascal Dao, Rafika Jarray, Johanne Le Coq et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 63 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +7