ECM1 Prevents Activation of Transforming Growth Factor β, Hepatic Stellate Cells, and Fibrogenesis in Mice - Concepedia

Concepedia

Publication | Open Access

ECM1 Prevents Activation of Transforming Growth Factor β, Hepatic Stellate Cells, and Fibrogenesis in Mice

DOI Full Paper Access

122

Citations

25

References

2019

Year

Weiguo Fan, Tianhui Liu, Wen Chen, Seddik Hammad, Thomas Longerich, Yadong Fu, Nan Li, Yajing He, Cui Liu, Yaguang Zhang,

Gastroenterology

Abstract

ECM1, produced by hepatocytes, inhibits activation of TGFB and its activation of HSCs to prevent fibrogenesis in mouse liver. Strategies to increase levels of ECM1 in liver might be developed for treatment of fibrosis.

References

	Year	Citations

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