Concepedia

Towards multi-target antidiabetic agents: Discovery of biphenyl-benzimidazole conjugates as AMPK activators

Denis A. Babkov, Olga N. Zhukowskaya, V. A. Babkova, E. V. Sokolova, A. A. Brigadirova, Roman Litvinov, Alexandra A. Kolodina, Vadim S. Sochnev

Bioorganic & Medicinal Chemistry Letters · 2019 · 46 citations · 23 references

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References

23

TLR4 links innate immunity and fatty acid–induced insulin resistance

Hang Shi, Maia V. Kokoeva, Karen Inouye et al. · Journal of Clinical Investigation · 2006 · 3.6K citations · Full text

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The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

Maria M. Mihaylova, Reuben J. Shaw · Nature Cell Biology · 2011 · 2.9K citations · Full text

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DataWarrior: An Open-Source Program For Chemistry Aware Data Visualization And Analysis

Thomas Sander, Joël Freyss, Modest von Korff et al. · Journal of Chemical Information and Modeling · 2015 · 1.8K citations

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Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome

Barbara L. Cool, Bradley A. Zinker, William J. Chiou et al. · Cell Metabolism · 2006 · 918 citations · Full text

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Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy

Robert W. Myers, Hong-Ping Guan, Juliann Ehrhart et al. · Science · 2017 · 344 citations

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