Publication | Closed Access

Bridging in vitro dissolution and in vivo exposure for acalabrutinib. Part II. A mechanistic PBPK model for IR formulation comparison, proton pump inhibitor drug interactions, and administration with acidic juices

Pharmaceutical ScienceVivo ExposureBiochemistryMedicineVitro DissolutionPharmacotherapyPharmacologyPharmacokineticsIr Formulation ComparisonPharmaceutical Research