G12V and G12C mutations in the gene KRAS are associated with a poorer prognosis in primary colorectal cancer

Kirsten ras Mutations in Patients With Colorectal Cancer: the Multicenter "RASCAL" Study

Jervoise Andreyev, Alyson Norman, Paul A. Clarke et al. · JNCI Journal of the National Cancer Institute · 1998 · 744 citations · Full text

Medicine, Genetics, Oncology +16

Biological properties of human c-Ha-ras1 genes mutated at codon 12

Peter H. Seeburg, Wendy W. Colby, Daniel J. Capon et al. · Nature · 1984 · 587 citations

Medicine, Genetics, Molecular Genetics +14

BRAF mutation is a powerful prognostic factor in advanced and recurrent colorectal cancer

Tomoya Yokota, Takashi Ura, Norio Shibata et al. · British Journal of Cancer · 2011 · 413 citations · Full text

Medicine, Oncology, Pathology +17

Frequency and type of KRAS mutations in routine diagnostic analysis of metastatic colorectal cancer

Jens Neumann, Evelyn Zeindl‐Eberhart, Thomas Kirchner et al. · Pathology - Research and Practice · 2009 · 358 citations

Medicine, Molecular Genetics, Oncology +16

Specific Mutations in <i>KRAS</i> Codons 12 and 13, and Patient Prognosis in 1075 <i>BRAF</i> Wild-Type Colorectal Cancers

Yu Imamura, Teppei Morikawa, Xiaoyun Liao et al. · Clinical Cancer Research · 2012 · 246 citations · Full text

Medicine, Molecular Genetics, Oncology +17