Cross-conjugated cyclopentenone prostaglandins synthesis of Δ7-10-chloro-15-deoxy PGA1 ethyl ester

A convenient synthesis of acetylenes: catalytic substitutions of acetylenic hydrogen with bromoalkenes, iodoarenes and bromopyridines

Kenkichi Sonogashira, Yasuo Tohda, Nobue Hagihara · Tetrahedron Letters · 1975 · 5.1K citations

Natural Sciences, Chemistry, Catalysis +11

Novel method for the synthesis of isomerically pure vinyl halides from alkynes via the hydroalumination reaction

George Zweifel, Charles C. Whitney · Journal of the American Chemical Society · 1967 · 169 citations

Natural Sciences, Chemistry, Mass Spectrometric Analysis +7

Chemical Implications for Antitumor and Antiviral Prostaglandins:  Reaction of Δ⁷-Prostaglandin A₁ and Prostaglandin A₁ Methyl Esters with Thiols

Masaaki Suzuki, Makoto Mori, Terutake Niwa et al. · Journal of the American Chemical Society · 1997 · 132 citations

Life Sciences, Biochemistry, Pharmacology +11

A general and stereocontrolled total synthesis of leukotriene B4 and analogs

K. C. Nicolaou, Robert E. Zipkin, Roland E. Dolle et al. · Journal of the American Chemical Society · 1984 · 91 citations

Natural Sciences, Chemistry, Medicinal Chemistry +6

Three-component coupling synthesis of prostaglandins. A simplified, general procedure

Masaaki Suzuki, Yasushi Morita, Hiroshi Koyano et al. · Tetrahedron · 1990 · 87 citations

Life Sciences, Biochemistry, Chemistry +3