Organic Letters · 2001 · 19 citations · 15 references
Life SciencesBiochemistryChemistryCarbohydrate BiochemistryCarbohydrate ChemistryCarbohydrate StructureCarbohydrate SynthesisGlycan BiosynthesisGlycan StructureGlycosidic Bond FormationMonosaccharide ChemistryCarbohydrate Building Block SynthesisDisaccharide SynthesisGlycoconjugate SynthesisMonosaccharide SynthesisOligosaccharide Synthesis
[reaction in text] A convergent strategy for the synthesis of beta-carba-galacto-disaccharides is illustrated by the preparation of 1 and 4, from a central "glycone" component 22, and the corresponding "aglycone" segments, monosaccharide alcohols, 23a or 23b. The key step is the formation of the carbasugar ring via an oxocarbenium ion-enol ether cyclization.
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