Concepedia

Michael Addition of Indole to α,β-Unsaturated Ketones Catalysed by Silica Sulfuric Acid under Ultrasonic Irradiation

Ji‐Tai Li, Hong‐Guang Dai, Wenzhi Xu, Tong‐Shuang Li

Journal of Chemical Research · 2006 · 11 citations · 11 references

DOI

Concepts

Abstract

Silica sulfuric acid catalyses the Michael addition of indole to α,β-unsaturated ketones under ultrasonic irradiation to afford the corresponding β-indolylketones in 50-85% yields at room temperature.

References

11

Silica sulfuric acid/NaNO2 as a novel heterogeneous system for production of thionitrites and disulfides under mild conditions

Mohammad Ali Zolfigol · Tetrahedron · 2001 · 420 citations

, , +13

Sequential One-Pot InBr<sub>3</sub>-Catalyzed 1,4- then 1,2-Nucleophilic Addition to Enones

Marco Bandini, Pier Giorgio Cozzi, Massimo Giacomini et al. · The Journal of Organic Chemistry · 2002 · 261 citations

, , +10

An efficient synthesis of 3,4-dihydropyrimidin-2-ones catalyzed by NH2SO3H under ultrasound irradiation

Ji‐Tai Li, Junfen Han, Jin‐Hui Yang et al. · Ultrasonics Sonochemistry · 2003 · 193 citations

, , +5

The Michael Addition of Indoles to α,β-Unsaturated Ketones Catalyzed by CeCl<sub>3</sub>·7H<sub>2</sub>O−NaI Combination Supported on Silica Gel<sup>1</sup>

Giuseppe Bartoli, Massimo Bartolacci, Marcella Bosco et al. · The Journal of Organic Chemistry · 2003 · 151 citations

, , +14

InCl3-Catalysed Conjugate Addition of Indoles with Electron-Deficient Olefins

J. S. Yadav, Sunny Abraham, B. V. Subba Reddy et al. · Synthesis · 2001 · 147 citations

, , +9