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InCl3-Catalysed Conjugate Addition of Indoles with Electron-Deficient Olefins
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2001
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Corresponding Michael AdductsEngineeringCatalytic AmountAlkene MetathesisCatalytic SynthesisOrganic ChemistryOrganometallic CatalysisCatalysisChemistryHigh SelectivityIncl3-catalysed Conjugate AdditionSynthetic ChemistryBiomolecular Engineering
Indole and 2-methylindole undergo conjugate addition with electron-deficient olefins in the presence of a catalytic amount of InCl3 at ambient temperature to afford the corresponding Michael adducts in excellent yields with high selectivity.