A new InCl3-catalyzed, facile and efficient method for the synthesis of spirooxindoles under conventional and solvent-free microwave conditions

100 years of the biginelli dihydropyrimidine synthesis

C. Oliver Kappe · Tetrahedron · 1993 · 1.2K citations

Natural Sciences, Chemistry, Medicinal Chemistry +8

Discovery of New Multi Component Reactions with Combinatorial Methods

Lutz Weber, Katrin Illgen, Michael Almstetter · Synlett · 1999 · 556 citations · Full text

Natural Sciences, Chemistry, Combinatorial Chemistry +15

Total Synthesis of Spirotryprostatin A, Leading to the Discovery of Some Biologically Promising Analogues

Scott D. Edmondson, Samuel J. Danishefsky, Laura Sepp‐Lorenzino et al. · Journal of the American Chemical Society · 1999 · 463 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Synthesis of halogen derivatives of benzo[h]chromene and benzo[a]anthracene with promising antimicrobial activities

Mostafa M. Khafagy, Ashraf Hassan Fekry Abd El‐Wahab, F. Eid et al. · Il Farmaco · 2002 · 454 citations

Natural Sciences, Chemistry, Medicinal Chemistry +10

Dihydropyrancarboxamides Related to Zanamivir:  A New Series of Inhibitors of Influenza Virus Sialidases. 1. Discovery, Synthesis, Biological Activity, and Structure−Activity Relationships of 4-Guanidino- and 4-Amino-4<i>H</i>-pyran-6-carboxamides

Paul W. Smith, Steven L. Sollis, Peter D. Howes et al. · Journal of Medicinal Chemistry · 1998 · 343 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17