Detection of plasmid-mediated tigecycline-resistant gene tet(X4) in Escherichia coli from pork, Sichuan and Shandong Provinces, China, February 2019

Abstract

The plasmid-mediated high-level tigecycline resistance gene, <i>tet</i>(X4), was detected in seven <i>Escherichia coli</i> isolates from pork in two Chinese provinces. Two isolates belonged to the epidemic spreading sequence type ST101. <i>Tet</i>(X4) was adjacent to IS<i>Vsa3</i> and concurrent with <i>floR</i> in all seven isolates. In addition to IncFIB, the replicon IncFII was found to be linked to <i>tet</i>(X4). This report follows a recent detection of <i>tet</i>(X3)/(X4) in <i>E. coli</i> from animals and humans in China.