Adropin regulates cardiac energy metabolism and improves cardiac function and efficiency

A central role for JNK in obesity and insulin resistance

Jiro Hirosumi, Gürol Tuncman, Lufen Chang et al. · Nature · 2002 · 3.3K citations

Medicine, Biochemistry, Endocrinology +14

The c-Jun NH2-terminal Kinase Promotes Insulin Resistance during Association with Insulin Receptor Substrate-1 and Phosphorylation of Ser307

Vincent Aguirre, Tohru Uchida, Lynne Yenush et al. · Journal of Biological Chemistry · 2000 · 1.5K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Insulin Resistance and Risk of Congestive Heart Failure

Erik Ingelsson, Johan Sundström, Johan Ärnlöv et al. · JAMA · 2005 · 581 citations

Medicine, Cardiology, Endocrinology +13

Reduced Cardiac Efficiency and Altered Substrate Metabolism Precedes the Onset of Hyperglycemia and Contractile Dysfunction in Two Mouse Models of Insulin Resistance and Obesity

Jonathan Buchanan, Pradip Kumar Mazumder, Ping Hu et al. · Endocrinology · 2005 · 544 citations · Full text

Life Sciences, Cardiology, Physiology +17

Insulin Resistance in Chronic Heart Failure: Relation to Severity and Etiology of Heart Failure

Jonathan W. Swan, Stefan D. Anker, C. Walton et al. · Journal of the American College of Cardiology · 1997 · 531 citations

Medicine, Cardiology, Endocrinology +12