A central role for JNK in obesity and insulin resistance

Jiro Hirosumi, Gürol Tuncman, Lufen Chang, +5

Nature

Insulin ResistanceMetabolic SyndromeObesityMetabolic DisorderInsulin Management +8

Functional <i>in vivo</i> interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance

Gürol Tuncman, Jiro Hirosumi, Giovanni Solinas, +3

Proceedings of the National Academy of Sciences

Metabolic DisorderMetabolic RemodelingTotal Jnk ActivityInsulin SignalingOxidative Stress +20

Purification and initial characterization of a protein which facilitates assembly of nucleosome‐like structure from mammalian cells

Yukio Ishimi, Jiro Hirosumi, Wakao Sato, +4

European Journal of Biochemistry

Exclusive Action of Transmembrane TNFα in Adipose Tissue Leads to Reduced Adipose Mass and Local But Not Systemic Insulin Resistance

Haiyan Xu, Jiro Hirosumi, K. Teoman Uysal, +2

Endocrinology

Inflammatory responses in cuff-induced atherosclerosis in rabbits

Jiro Hirosumi, Atsushi Nomoto, Y. Ohkubo, +4

Atherosclerosis

InflammationInflammatory ResponsesImmunologyEndothelial DysfunctionVascular Biology +3

Pharmacological characteristics of a novel nonthiazolidinedione insulin sensitizer, FK614

Hideaki Minoura, Shigeru Takeshita, Makoto Ita, +14

European Journal of Pharmacology

Molecular PharmacologyPharmacological CharacteristicsBiochemistryMedicineInsulin Management +5

Antiatherogenic activity of FR34235 (Nilvadipine), a new potent calcium antagonist

Atsushi Nomoto, Jiro Hirosumi, Chie Sekiguchi, +3

Atherosclerosis

Antiatherogenic ActivityMedicinePhysiologyPharmacotherapyPharmacology +1

A Protein which Facilitates Assembly of Nucleosome-Iike Structures In Vitro in Mammalian Cells1

Yukio Ishimi, Hideyo Yasuda, Jiro Hirosumi, +2

The Journal of Biochemistry

FK143, a novel nonsteroidal inhibitor of steroid 5α-reductase: (1) In vitro effects on human and animal prostatic enzymes

Jiro Hirosumi, O. Nakayama, TC Fagan, +7

The Journal of Steroid Biochemistry and Molecular Biology

Animal Prostatic EnzymesNovel Nonsteroidal InhibitorUrologyBiochemistryMedicine +6

Effect of superoxide and lipid peroxide on cytosolic free calcium concentration in cultured pig aortic endothelial cells

Jiro Hirosumi, Yasuyoshi Ouchi, Masae Watanabe, +3

Biochemical and Biophysical Research Communications

Vascular AdaptationLipid PeroxidationPhysiologyExtracellular MatrixEndothelial Dysfunction +8