Simultaneous isotope dilution quantification and metabolic tracing of deoxyribonucleotides by liquid chromatography high resolution mass spectrometry

Stimulation of de Novo Pyrimidine Synthesis by Growth Signaling Through mTOR and S6K1

Issam Ben‐Sahra, Jessica J. Howell, John M. Asara et al. · Science · 2013 · 714 citations

MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer

Surendra K. Shukla, Vinee Purohit, Kamiya Mehla et al. · Cancer Cell · 2017 · 531 citations · Full text

Tumor Biology, Impart Gemcitabine Resistance, Pancreatic Cancer +7

A naturally occurring antiviral ribonucleotide encoded by the human genome

Anthony S. Gizzi, Tyler L. Grove, Jamie J. Arnold et al. · Nature · 2018 · 316 citations

Viral Replication, Natural Sciences, Dna Replication +6

Suppression of Nucleotide Metabolism Underlies the Establishment and Maintenance of Oncogene-Induced Senescence

Katherine M. Aird, Gao Zhang, Hua Li et al. · Cell Reports · 2013 · 290 citations · Full text

Oncogene-induced Senescence, Reductive Stress, Genome Instability +15

Metformin Targets Central Carbon Metabolism and Reveals Mitochondrial Requirements in Human Cancers

Xiaojing Liu, Iris L. Romero, Lacey M. Litchfield et al. · Cell Metabolism · 2016 · 237 citations · Full text

Central Carbon Metabolism, Mitochondrial Function, Biochemistry +13