Rhombenone: farnesyl protein transferase inhibitor from the leaves of Hedera rhombea Bean

Inhibition of purified p21 farnesyl:protein transferase by Cys-AAX tetrapeptides

Yuval Reiss, Joseph L. Goldstein, Miguel C. Seabra et al. · Cell · 1990 · 815 citations

Life Sciences, Biochemistry, Molecular Biology +9

Benzodiazepine Peptidomimetics: Potent Inhibitors of Ras Farnesylation In Animal Cells

Guy L. James, Joseph L. Goldstein, Michael S. Brown et al. · Science · 1993 · 629 citations

Medicine, Oncology, Pharmacology +15

Selective Inhibition of <i>ras</i> -Dependent Transformation by a Farnesyltransferase Inhibitor

Nancy E. Kohl, Scott D. Mosser, S. J. DESOLMS et al. · Science · 1993 · 582 citations

Medicine, Oncology, Pharmacology +13

Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice

Nancy E. Kohl, Charles A. Omer, Michael W. Conner et al. · Nature Medicine · 1995 · 539 citations

Medicine, Cancer Biology, Oncology +11

Studies on the Constituents of Japanese and Chinese Crude Drugs. XI. Panaxadiol, A Sapogenin of Ginseng Roots. (1).

Shoji Shibata, Mitiiti Fujita, Hideji Itokawa et al. · Chemical and Pharmaceutical Bulletin · 1963 · 136 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +11