Syntheses of 5‐hydroxy‐2‐(phenyl or styryl)chromones and of some halo derivatives

Abstract

Abstract One‐pot syntheses of 5‐hydroxy‐2‐(phenyl or styryl)chromones and the corresponding 6‐ and 8‐monoiodo‐ and 6,8‐diiodochromones have been developed. The procedures involve oxidative cyclization of 2′‐benzyloxy‐6′‐hydroxychalcones and 2′‐benzyloxy‐6′‐hydroxy‐2‐cinnamylideneacetophenones and electrophilic substitution processes on the chromone moieties; such procedures were also applied to the syntheses of 6,8‐dibromochromone derivatives.