SAR studies in the sulfonyl carboxamide class of HBV capsid assembly modulators

Specific and Nonhepatotoxic Degradation of Nuclear Hepatitis B Virus cccDNA

Julie Lucifora, Yuchen Xia, Florian Reisinger et al. · Science · 2014 · 874 citations · Full text

Pharmacy, Molecular Biology, Molecular Medicine +17

Inhibition of Hepatitis B Virus Replication by Drug-Induced Depletion of Nucleocapsids

Karl Deres, Claus H. Schröder, Arnold Paessens et al. · Science · 2003 · 506 citations

Medicine, Pharmacology, Pharmacotherapy +17

Serum hepatitis B virus RNA is encapsidated pregenome RNA that may be associated with persistence of viral infection and rebound

Jie Wang, Tao Shen, Xiangbo Huang et al. · Journal of Hepatology · 2016 · 445 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Inhibition of human hepatitis B virus (HBV) by a novel non-nucleosidic compound in a transgenic mouse model

Olaf Weber, K.-H. Schlemmer, Enno Hartmann et al. · Antiviral Research · 2002 · 162 citations

Life Sciences, Medicinal Chemistry, Molecular Biology +9

HBc binds to the CpG islands of HBV cccDNA and promotes an epigenetic permissive state

Yanhai Guo, Yong-Nian Li, Jinrong Zhao et al. · Epigenetics · 2011 · 149 citations · Full text

Medicine, Genetics, Molecular Biology +14