Concepedia

Tetrahydro-3-benzazepines with fluorinated side chains as NMDA and σ1 receptor antagonists: Synthesis, receptor affinity, selectivity and antiallodynic activity

Simone Thum, Dirk Schepmann, Eva Ayet, Marta Pujol, Francisco R. Nieto, Simon M. Ametamey, Bernhard Wünsch

European Journal of Medicinal Chemistry · 2019 · 11 citations · 37 references

DOIFull text

Open access

Concepts

References

37

Sigma-1 Receptor Chaperones at the ER- Mitochondrion Interface Regulate Ca2+ Signaling and Cell Survival

Teruo Hayashi, Tsung‐Ping Su · Cell · 2007 · 1.8K citations · Full text

, , +14

Subunit arrangement and function in NMDA receptors

Hiroyasu Furukawa, Satinder K. Singh, Romina Mancusso et al. · Nature · 2005 · 767 citations

, , +14

A proposal for the classification of sigma binding sites

Rémi Quirion, Wayne D. Bowen, Yossef Itzhak et al. · Trends in Pharmacological Sciences · 1992 · 754 citations

, , +7

Sigma-1 and sigma-2 receptors are expressed in a wide variety of human and rodent tumor cell lines.

Bertold J. Vilner, Christy S. John, W D Bowen · PubMed · 1995 · 488 citations

, , +10

Crystal structure of the human σ1 receptor

Hayden R. Schmidt, Sanduo Zheng, Esin Gurpinar et al. · Nature · 2016 · 466 citations · Full text

, , +14