Eva Ayet

Discovery of EST73502, a Dual μ-Opioid Receptor Agonist and σ₁ Receptor Antagonist Clinical Candidate for the Treatment of Pain

Mónica Garcı́a, Marina Virgili, Mónica Alonso et al. · Journal of Medicinal Chemistry · 2020 · 37 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Oleoyl-estrone is a precursor of an estrone-derived ponderostat signal

Ruth Vilà, Cristina Cabot, Laura Villarreal et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2011 · 11 citations · Full text

Life Sciences, Biochemistry, Pharmacology +10

Tetrahydro-3-benzazepines with fluorinated side chains as NMDA and σ1 receptor antagonists: Synthesis, receptor affinity, selectivity and antiallodynic activity

Simone Thum, Dirk Schepmann, Eva Ayet et al. · European Journal of Medicinal Chemistry · 2019 · 11 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Bispecific sigma-1 receptor antagonism and mu-opioid receptor partial agonism: WLB-73502, an analgesic with improved efficacy and safety profile compared to strong opioids

Alba Vidal‐Torres, Begoña Fernández‐Pastor, Mónica Garcı́a et al. · Acta Pharmaceutica Sinica B · 2022 · 10 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17