Oxidative stress-induced IL-15 trans-presentation in keratinocytes contributes to CD8+ T cells activation via JAK-STAT pathway in vitiligo

Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition

Luzhou Xing, Zhenpeng Dai, Ali Jabbari et al. · Nature Medicine · 2014 · 953 citations · Full text

Medicine, Dermatology, Immunology +16

IL-15Rα Recycles and Presents IL-15 In trans to Neighboring Cells

Sigrid Dubois, Jennifer Mariner, Thomas A. Waldmann et al. · Immunity · 2002 · 889 citations · Full text

Life Sciences, Cell Biology, Immunology +10

The role of shared receptor motifs and common stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15

Jian-Xin Lin, Thi-Sau Migone, Monica Tseng et al. · Immunity · 1995 · 752 citations · Full text

Life Sciences, Immunology, Molecular Biology +15

CD49a Expression Defines Tissue-Resident CD8 + T Cells Poised for Cytotoxic Function in Human Skin

Stanley Cheuk, Heinrich Schlums, Irène Gallais Sérézal et al. · Immunity · 2017 · 652 citations · Full text

Life Sciences, Dermatology, Immunology +17

Autoimmune Destruction of Skin Melanocytes by Perilesional T Cells from Vitiligo Patients

Jasper G. van den Boorn, Debby Konijnenberg, Trees A. M. Dellemijn et al. · Journal of Investigative Dermatology · 2009 · 524 citations · Full text

Life Sciences, Dermatology, Immunology +16