Cancer statistics, 2016

Rebecca L. Siegel, Kimberly D. Miller, Ahmedin Jemal

CA A Cancer Journal for Clinicians

Cofactor Dynamics and Sufficiency in Estrogen Receptor–Regulated Transcription

Yongfeng Shang, Xiao Hu, James DiRenzo, +2

Cell

Transcriptional RegulationNatural SciencesHormonal ReceptorTranscription RegulationGene Regulation +6

UHRF1 Plays a Role in Maintaining DNA Methylation in Mammalian Cells

Magnolia Bostick, J. Kim, Pierre‐Olivier Estève, +3

Science

Histone ModificationsEpigenetic ChangeGeneticsDna MethylationGenomic Mechanism +17

The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA

Jafar Sharif, Masahiro Muto, Shin‐ichiro Takebayashi, +11

Nature

ChromatinEpigenetic InheritanceChromatin RemodelingNatural SciencesGenetics +11

The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin

Lisa M. Butler, Xianbo Zhou, Weisheng Xu, +4

Proceedings of the National Academy of Sciences

Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism

Kyohei Arita, Mariko Ariyoshi, Hidehito Tochio, +2

Nature

ChromatinSra Protein Uhrf1Chromatin RemodelingHemi-methylated DnaGenetics +11

The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix

Hideharu Hashimoto, J.R. Horton, Xing Zhang, +3

Nature

ChromatinUhrf1 FlipsChromatin RemodelingDna HelixNatural Sciences +10

UHRF1 Overexpression Drives DNA Hypomethylation and Hepatocellular Carcinoma

Raksha Mudbhary, Yujin Hoshida, Yelena Chernyavskaya, +16

Cancer Cell

ChromatinTumor SuppressorCancer GeneticsMedicineRadiation Oncology +3

ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain

Motoko Unoki, Toshihiko Nishidate, Yusuke Nakamura

Oncogene

E2f-1 TargetProtein FunctionSignal TransductionSignaling PathwaySignal Recognition +5

VDUP1 upregulated by TGF-β1 and 1,25-dihydorxyvitamin D3 inhibits tumor cell growth by blocking cell-cycle progression

Seung Hyun Han, Jun Ho Jeon, Hyang Ran Ju, +10

Oncogene

Tumor BiologyMedicineCancer Cell BiologyCell ProliferationCell-cycle Progression +6