The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA

Jafar Sharif, Masahiro Muto, Shin‐ichiro Takebayashi, +11

Nature

ChromatinEpigenetic InheritanceChromatin RemodelingNatural SciencesGenetics +11

Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication

Atsuya Nishiyama, Luna Yamaguchi, Jafar Sharif, +9

Nature

ChromatinChromatin RemodelingNatural SciencesGeneticsEpigenetic Change +5

An Evolutionarily Conserved Mechanism for MicroRNA-223 Expression Revealed by MicroRNA Gene Profiling

Taro Fukao, Y. Fukuda, Kotaro Kiga, +7

Cell

Microrna Gene ProfilingMedicineGeneticsGene ExpressionEvolutionarily Conserved Mechanism +8

Targeting Polycomb to Pericentric Heterochromatin in Embryonic Stem Cells Reveals a Role for H2AK119u1 in PRC2 Recruitment

Sarah Cooper, Martin Dienstbier, Raihann Hassan, +9

Cell Reports

Prc2 RecruitmentGeneticsDna MethylationEpigenetic ChangeCpg Hypomethylation +19

SAM Domain Polymerization Links Subnuclear Clustering of PRC1 to Gene Silencing

Kyoichi Isono, Takaho A. Endo, Manching Ku, +7

Developmental Cell

EngineeringCross-linkComputational BiologyMolecular BiologyNucleic Acid Amplification +4

Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells

Jiho Choi, Aaron J. Huebner, Kendell Clement, +20

Nature

Developmental BiologyCell DivisionMedicineAdult Stem CellDevelopmental Potential +8

Histone H2A Mono-Ubiquitination Is a Crucial Step to Mediate PRC1-Dependent Repression of Developmental Genes to Maintain ES Cell Identity

Mitsuhiro Endoh, Takaho A. Endo, Tamie Endoh, +10

PLoS Genetics

Histone ModificationsDevelopmental GenesEpigenetic ChangeGeneticsEpigenetics +22

The epigenetic regulator Uhrf1 facilitates the proliferation and maturation of colonic regulatory T cells

Yuuki Obata, Yukihiro Furusawa, Takaho A. Endo, +19

Nature Immunology

ChromatinEpigenetic Regulator Uhrf1Lineage PlasticityDevelopmental BiologyCell Regulation +10

Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality

Sònia Sabaté‐Soler, Sarah Nickels, Cláudia Saraiva, +13

Glia

PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes

Mitsuhiro Endoh, Takaho A. Endo, Jun Shinga, +16

eLife