Expression, purification, and characterization of the Degludec precursor DesB30

IDF Diabetes Atlas: Global estimates for the prevalence of diabetes for 2015 and 2040

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Medicine, Chronic Disease Prevention, Endocrinology +12

The disulphide bonds of insulin

A. Ryle, Frederick Sanger, L. Smith et al. · Biochemical Journal · 1955 · 930 citations · Full text

Life Sciences, Biochemistry, Enzymology +8

Characterization of the Oligomeric States of Insulin in Self-Assembly and Amyloid Fibril Formation by Mass Spectrometry

Ewan J. Nettleton, Paula Tito, Margaret Sunde et al. · Biophysical Journal · 2000 · 288 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Application of simple fed-batch technique to high-level secretory production of insulin precursor using Pichia pastoris with subsequent purification and conversion to human insulin

Chandrasekhar Gurramkonda, Sulena Polez, Nataša Skoko et al. · Microbial Cell Factories · 2010 · 104 citations · Full text

Life Sciences, Biochemistry, Biotechnology +13

Secretory expression and characterization of insulin in <i>Pichia pastoris</i>

Thomas Kjeldsen, A. Pettersson, Morten Hach · Biotechnology and Applied Biochemistry · 1999 · 87 citations

Life Sciences, Biochemistry, Molecular Biology +13