Acyl-CoA-Binding Protein Drives Glioblastoma Tumorigenesis by Sustaining Fatty Acid Oxidation

Fiji: an open-source platform for biological-image analysis

Johannes Schindelin, Ignacio Arganda‐Carreras, Erwin Frise et al. · Nature Methods · 2012 · 70.9K citations

Engineering, Bioinformatics, Biology +9

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Goberdhan P. Dimri, X Lee, George Basile et al. · Proceedings of the National Academy of Sciences · 1995 · 7.4K citations · Full text

Education, Cell Biology, Molecular Biology +15

The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs

Yi Zhu, Tamar Tchkonia, Tamar Pirtskhalava et al. · Aging Cell · 2015 · 2.4K citations · Full text

Life Sciences, Cell Biology, Pharmacology +17

Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

Jeongwu Lee, Svetlana Kotliarova, Yuri Kotliarov et al. · Cancer Cell · 2006 · 2.3K citations · Full text

Medicine, Cell Biology, Oncology +16

Senolytics improve physical function and increase lifespan in old age

Ming Xu, Tamar Pirtskhalava, Joshua N. Farr et al. · Nature Medicine · 2018 · 2.2K citations

Education, Geriatric Medicine, Physiology +14