Loss of NFBD1/MDC1 disrupts homologous recombination repair and sensitizes nasopharyngeal carcinoma cells to PARP inhibitors - Concepedia

Concepedia

Publication | Open Access

Loss of NFBD1/MDC1 disrupts homologous recombination repair and sensitizes nasopharyngeal carcinoma cells to PARP inhibitors

DOI Full Paper Access

13

Citations

25

References

2019

Year

Zhihai Wang, Wenqi Zuo, Quan Zeng, Qian Yi, Yanshi Li, Chuan Liu, Jue Wang, Shixun Zhong, Youquan Bu, Guohua Hu

Journal of Biomedical Science

Abstract

We show that NFBD1 depletion may possess sensitizing effects of PARP inhibitor, and consequently offers novel therapeutic options for a significant subset of patients.

References

	Year	Citations

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